Effectiveness of Eight Weeks Aerobic Training and Nano Curcumin Supplementation on Serum Amyloid A Protein Content and Body Composition in Overweight and Obese Women

Introduction: Serum Amyloid A (SAA) is a sensitive marker related to the acute inflammatory phase, produced in the liver, and has got the protection and repair role in the inflammatory process. Nano curcumin (turmeric pigment) is anti-inflammatory and antioxidant. The purpose of this study was to evaluate the impact of advanced aerobic training and Nano curcumin supplementation on body composition and SAA levels in overweight and obese women. Methods: In this quasi-experimental study،The Forty-Four women with (age 28.7 ± 3.33 years, BMI 31.53 ± 4.86 kg/m2 and WHR 0.82 ± 0.07 cm) above 25 kg/m2 were selected purposefully and were randomly divided into four groups of advanced aerobic training (n = 12), advanced aerobic training+ Nano curcumin (n = 12), Nano curcumin (n = 10) and control (n = 10) and for 8 weeks, they performed advanced aerobic exercise and daily intake of a Nano curcumin 80 m/g nanomicelle capsule. The Nano curcumin and control groups had no physical activity during the period. Fasting blood samples were taken 24 hours before and 48 hours after the last training session and serum levels were measured by ELISA using human kits. For data normality, K-S test and dependent t-test and analysis of ANOVA were used to test the hypothesis. Results: The results showed that eight weeks of training ،supplementation ،and train +supplementation group significantly decreased SAA about pre-exercise values (P =0.001) There was also a significant difference between the four groups (P < 0.05).Conclusions: Improved aerobic exercise and Nano curcumin appear to be effectivein reducing the inflammatory status of overweight and obese women as well as inreducing body weight by reducing inflammatory factors.